# GEF-GAP-Competition-Simulator

Repository for the paper Bimodality in Ras signaling originates from processivity of the Ras activator SOS without classic kinetic bistability.
This repository stores the source codes of the programs used to model the stochastic Ras GEF-GAP competition reaction studied in the paper.
GEF and GAP models SOS and p120, respectively.

## Code requirements:
- Symbolic Math Toolbox.
- Statistics and Machine Learning Toolbox.

## Scripts

Three scripts are provided under src\.

1. mainScript.m
2. gefInhibitorSimulationScript.m
3. gefConcentrationTitrationScript.m

## Acknowledgements
This project makes use of several external resources:
- Hartigans Dip Test as implemented by Ferenc Mechler, 2002; and retrieved from http://nicprice.net/diptest/
- Error Handling routines as provided by Mark Hayworth 2017; and retrieved from https://www.mathworks.com/matlabcentral/fileexchange/24224-magic-matlab-generic-imaging-component
